Tag Archives: B12 injection

You are tired?

K. C. is a 43 year old female who came into the clinic with fatigue as well as recent clouded memory particularly poor name recollection. She was also interested in starting a series of vitamin B12 injections to help with her symptoms. The patient had no prior medical history to date; in fact, she is a yoga instructor who alternates between a pescatarian and vegetarian diet. The patient typically wakes up in the early morning but doesn’t eat breakfast for several hour. Her energy level is generally 3/10 with 10 being highest in energy. The first suggestion was to eat more protein and fiber in the early morning. She was recommended to increase fiber through ground flax and protein through eggs or beans, and to start to incorporate maca powder. Maca powder has a variety of health benefits including B12 and E vitamins, calcium, supplies iron and helps restore red blood cells, which in turn increase energy levels. In addition to dietary changes, blood tests were done to find out if the fatigue is from anemia or poor thyroid function. Also, although the patient lives and works in parts of the world with sun, a vitamin D test was run. The lab results showed that she fell in the normal ranges for the general blood testing, yet deficiencies in vitamin D and extremely low levels of ferritin. Ferritin is a protein found inside cells that stores iron so the body can use it later. In order to help with energy levels, she got a series of vitamin B12 shot, a direct injection of vitamin B12 which helps with energy and memory boosting if levels are too low in the blood. She also started taking 4000 IU of vitamin D3 daily with a fatty food such as avocado. For thyroid stability, she started increasing iodine through eating more iodine rich foods such as seaweed.  Lastly, increasing iron will restore red blood cells and increase energy so she started taking an iron support with extra vitamin C to help with iron absorption. She also started a series of iron injection.

Now, after 2 weeks of dietary changes along with weekly injections, her energy is 9/10.

For more information about naturopathic care with Dr. Lee, please visit Seattle Naturopathic and Acupuncture Center or call 206-319-5322

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How does lipotropic injections help with weight loss?

Lipotropic nutrients are a class of natural ingredients that play important roles in the body’s use of fat. These compounds enhance liver and gallbladder’s role by decreasing fat deposits and speeding up metabolism of fat and its removal. Dr. Lee has used this special formula for individuals who are “stuck” in their weight loss attempts and need that extra boost to achieve their goal weight. This injection has also been gratefully used for individuals who want to maintain their weight, or prevent re-gain of their lost weight. The main ingredients in the lipotropic injection are methionine, inositol, and choline. Some individuals will also benefit the addition of vitamin B12.

 

 

Methionine

assists in the breakdown of fats and thereby prevents the build-up of fat in the arteries, as well as assisting with the digestive system and removing heavy metals from the body since it can be converted to Cytosine, which is a precursor to Glutathione, which is of prime importance in detoxifying the liver.

 

Inositol

helps to maintain proper electrical energy and nutrient transfer across the cell membrane. It also acts as a lipotropic which converts fats into other useful products. Inositol helps establish healthy cell membranes, which facilitate nerve impulses.

 

Choline

Assists in controlling your weight as well as cholesterol levels, keeping cell membranes healthy and in preventing gallstones. It is also most useful in the maintenance of the nervous system, assisting memory and learning, and may help to fight infections, including hepatitis and AIDS. Choline is critical for normal membrane structure and function. Choline is the major precursor of betaine, and it is used by the kidneys to maintain water balance and by the liver as a source of methyl-groups for Methionine formation. It is also used to produce the important neurotransmitter Acetylcholine. It assists in nerve impulse transmission, gallbladder regulation, liver functions and lecithin production.

 

B-12

is a vitamin which is important for the normal functioning of the brain and nervous system, and for the formation of blood. It is normally involved in the metabolism of every cell of the body, especially affecting DNA synthesis and regulation, but also fatty acid synthesis and energy production.

 

For more information about lipotropic injections or if you would like to schedule, please call 206-319-5322 or visit Seattle Naturopathic and Acupuncture Center for more information.

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Confused by the different types of vitamin B12?

Looking for a safe and effective way to reduce to optimize health? The answer would be to eat right and exercise. One can also consider vitamin B12 injections as it can give you positive results as well.

Vitamin B12, also known as cobalamin, is a water-soluble vitamin. It is a nutrient that is important for cell proliferation, nerve health, and carbohydrate metabolism. It is an essential nutrient needed to make red blood cells that carry oxygen throughout the body, the myelin sheath that surrounds nerve cells, and various proteins. It also plays a role in fat and carbohydrate metabolism.

As vitamin B12 injection is getting more popular, there is also the question of which type of B12 to get.

Hydroxocobalamin B12 is a natural and uniquely powerful form of vitamin B12. Clinical studies practice have shown it can help to improve cognitive function, fight fatigue, promote heart health and more. Studies have found that hydroxocoblamin raises B12 levels higher and lasts longer than cyanocobalamin (1,2). Hydroxocobalamin has a high affinity for cyanide. It pulls the cyanide out of the mitochondria of the cell and combines with it to form cyanocobalamin, which is then excreted in the urine. In 2006, hydroxocobalamin was approved by the FDA as an antidote for cyanide poisoning. Since cyanide is present in cigarette smoke  (and essentially reduces the cells’ ability to use oxygen), hydroxocobalamin would be a good option for smoker seeking a B12 supplement.

On the other hand, methylcobalamin may be help in preventing and treating chronic fatigue syndrome, Parkinson’s disease, peripheral neuropathies, Alzheimer’s disease, muscular dystrophy and neurological aging.

The most common form of vitamin B12 is called cyanocobalamin. However, over the last ten years, a number of central peripheral neurological diseases have been linked to a deficiency of a very specific cobalamin, the methylcobalamin form, that is required to protect against neurological disease and aging. The liver converts a small amount of cyanocobalamin into methylcobalamin within the body, but larger amounts of methylcobalamin are necessary to correct neurological defects and protect against aging.

Few substances have been shown to regenerate nerves in humans with peripheral neruopathies. However, a study in the Journal of Neurological Science postulated that methylcobalamin could increase protein synthesis and help regenerate nerves. The scientists showed that very high doses of methylcobalamin produce nerve regeneration in laboratory rats. The scientists stated that ultra-high doses of methylcobalamin might be of clinical use for patients with peripheral neuropathies.

1. Hall CA, et al. “The availability of therapeutic hydroxocobalamin to cells.” Blood. 1984 Feb;63(2):335-41.
2. Glass GBJ, et al. “Hydroxocobalamin V. Prolonged maintenance of high vitamin B12 blood levels following a short course of hydrooxocobalamin injections.” Blood. 1966. Vol 27, No. 2 pp 234-241.

Interested in B12 injection. Visit  Seattle Naturopathic and Acupuncture Center or call 206-319-5322.

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Factors affecting B12 absorption

Animal products (meat and dairy products) provide the onlydietary source of vitamin B12 for humans. Since B12 is only found in animal sources, vegans and vegetarians are sometimes deficient in B12. The elderly are also more likely to suffer from B12 deficiencies due to multiple steps involved in B12 absorption. People who have a difficult time absorbing B12 may suffer from a condition called pernicious anemia. The usual western diet contains 5 to 7 micrograms of vitamin B12 per day, while the minimum daily requirement is listed as 6 to 9 micrograms per day. Approximately one-half of the total body store is in the liver.

Dietary B12 in the presence of acid and pepsin in the stomach is released from the food and then quickly binds to R factors in saliva and gastric juice. Vitamin B12 bound to R factors is not absorbed. Absorption occurs in the alkaline environment of the duodenum. In this alkaline environment, vitamin B12 is freed from R proteins by pancreatic proteases and then binds specifically and rapidly to gastric-derived intrinsic factor. Intrinsic factor has very high affinity for vitamin B12. The intrinsic factor-vitamin B12 complex binds to specific intestinal receptors and it is absorbed in an energy requiring process that is still incompletely understood.

Thus, adequate absorption of vitamin B12 depends upon five factors.

  • · Dietary intake (aim for healthy meat such as fish or chicken or choose egg or dairy items)
  • Proper acid-pepsin in the stomach to release B12 from binding to food particles.
  • Pancreatic proteases to free B12 from binding to R factors
  • Secretion of intrinsic factor by the gastric parietal cells in the stomach to bind to B12
  • An ileum (specific section of the small intestine) with vitamin B12-intrinsic factor receptors.

Once taken up by the specific intestinal cells, the vitamin B12 travels along the blood stream by binding to transcobalamin II. This complex binds to specific cell surface receptors in order to enter the cell. Vitamin B12 in the cells is metabolized into two coenzymes: adenosyl-cobalamin; and methyl-cobalamin. It is crucial that every single step along the way is working adequately in order for vitamin B12 to be absorbed properly.

Finally, other medications can interfere with vitamin B12 absorption. The University of Maryland Medical Center claims that some medications used to control diabetes and cholesterol, as well as chemotherapy medications, antibiotics and anticonvulsants, can reduce your ability to absorb vitamin B12.

For more information about vitamin B12 supplementation or injections, please contact Dr. Lee via email info@seattlenaturopathiccenter.com or 206-319-5322. Don’t forget to ask about B12 happy hour where B12 injections are only $12.

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