Category Archives: epigenetic

Basic summary on MTFHR mutation detrimental health effects

Multiple studies have been conducted on the subject of MTFHR mutations and their impact on how our body work on a daily basis. MTHFR’s function in our body is to perform a process called methylation inside our cells. By doing so, MTHFR can help create, convert, and alter compounds within our cells. Methylation impacts many processes. It is involved in cellular repair and the production of DNA. It helps with neurotransmitter production and it is also vital in the formation and development of red blood cells, white blood cells, platelets, and the maintenance of a healthy immune system.

Research studies including “Assocation between MTHFR C677T polymorphism and depression: an updated meta-analysis of 26 studies” and  “ Angiotensin converting enzyme and MTFHR gene variations in fibriomyalgia syndrome” have found that there is in fact a strong link between MTFHR variations and detrimental health conditions such as depression, chronic fatigue and fibromyalgia, among others. These studies have also shown that active forms of vitamin B12 and folinic acid are helpful in treating the negative effects of the mutation.

Today, over 60% of the world’s population has a vartiation on their MTHFR gene. Although some people never present negative side effects or health conditions due to this muation, an increasing number of people suffer consequences from the mutation. This in part is because epigenetic plays a huge role. Epigenetic is the non-genetic influence of gene expression.  Simply put, our diet, stress levels, environment, lifestyle can have an impact on how the gene is expressed. Screening for MTFHR mutation is highly recommended for all patients who suffer from chronic mental, neurological, pain conditions such as depression, anxiety, fibromyalgia, and ADHD, as well as histamine related conditions such as hives and itchy skin.

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Filed under Allergies, B 12 injection, epigenetic, fatigue, gene, seattle naturopath, Uncategorized

Trends in Food Allergy Research

Study: Trends in Food Allergy Research by JUNKO SHIMADA (Life Science and Medical Research Unit)

 
This week is “National Healthy Eating Week” and I wanted to share with all of you some important insights related to food allergy research. A study conducted by Junko Shimada at the Life Science and Medical Research Unit, regarding important trends in food allergies suggests that the incidence of allergic diseases such as food allergy, atopic dermatitis, bronchial asthma and cedar pollenosis continues to increase in developed countries such as the United States. In particular, food allergy, which is often developed during infancy, and can affect a child’s growth or trigger an “allergic march,” or in other words, the progressive development of multiple allergies.

 
Currently, it is estimated that over 15 million Americans suffer from food allergies and food sensitivity. Data has also shown that 1 in 13 children are affected by at least 1 food allergy in their lifetime. Now you may be wondering what exactly is a food allergy? Food allergy is an exaggerated immune response induced by the misrecognition of orally ingested food as a foreign substance. Some of the most common food allergies include but are not limited to: eggs, milk, wheat, beans, buckwheat, fruit, seafood and meat. The development of food allergy involves both genetic and environmental factors such as pollution, food contamination, and chemical preservatives added to the different food products. Food allergies cause a hypersensitive reaction that damages our various systems, with symptoms that can include diarrhea, abdominal pain, hives and eczema. Severe cases of food allergy can induce anaphylactic shock, which may lead to death. The best way to stay safe and healthy is to become aware of potential existing allergies and food sensitivities by getting tested! If you would like to learn more information regarding this topic or if you’d like to get tested you can call our office at Seattle Naturopathic and Acupuncture Center and our team we’ll be happy to help you schedule an appointment.

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Filed under Allergies, Arthritis, Digestion, Eczema, epigenetic, fatigue, Food allergy, headaches, IBD, IBS, Leaky gut syndrome, Weight Loss

Genes and diet: making healthier choices lower the chances of detrimental gene expression changes

Let’s talk about Epigenetics! The field of Epigenetics studies the different changes in organisms caused by the modification of gene expression rather than alteration in the genetic code itself. Now, you may be wondering how is this field relevant to you, your health and your everyday life style choices? Environmental factors such as your daily diet, smoking patterns and stress levels have been shown to impact gene expression through epigenetic mechanisms. In other words, research studies suggest that your lifestyle habits directly impact your organism and the way your genes are expressed.

Let’s take a look at one particular study that focused on testing this idea! A recent experiment performed by BMC Physiology scientists on mice, had the purpose of determining how their immune system responded to a typical Western diet. When mice were fed a Western diet, systemic inflammation occurred which was entirely expected. However, what was particularly interesting was that the Western diet fundamentally changed their immune system. After eating a high calories, low nutrient food, not only did the mice exhibit more systemic inflammation, but their white blood cells became programmed to remain hyper-sensitive to inflammatory triggers. In other words, their diet caused a drastic change tot their cellular “memory”, making their cells more vulnerable to inflammatory responses. These results may help explain why chronic inflammation is behind so many lifestyle-related diseases such as heart disease, obesity and diabetes. Studies like this one and many others conducted recently, show significant evidence that demonstrate the impact that your environment and life style choices have on your body. They also suggest that making healthier choices lower the chances of detrimental gene expression changes.

 
If you’d like to learn more about ways to improve your diet or get tested for food
allergies, give Seattle Naturopathic and Acupuncture Center a call and we’d be happy to schedule an appointment for you!

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Filed under decrease pain, Digestion, epigenetic, Food allergy, gene, IBD, IBS, Inflammation, Leaky gut syndrome, Uncategorized